"Azaspiracids: Toxicological Evaluation, Test Methods and Identification of the Source Organism"
Research Measure: Industry Research Measure
Funding Type: NDP Marine Research Sub-Programme
Funding Year: 2008
Project Duration: 40 months
Project Type: Project-Based Award
Total Grant-Aid: €1,020,699
Lead Partner: MEFSS, Marine Institute
Project Partners:
- Norwegian School of Veterinary Science, Norway
- National Oceanic & Atmospheric Administration, USA
- National Research Council, Canada
- Alfred Wegener Institute, Germany
- Dublin Institute of Technology, Ireland
- Ifremer, France
Project Summary:
This project aims to strengthen the existing monitoring programme for shellfish toxins through (i) the elucidation of the source organism of azaspiracids; (ii) the clarification of relative and combined toxicities and the mode of action of analogues of azaspiracids and other lipophilic toxins; and (iii) the sustainable supply of AZA-calibrants in support of international efforts in the validation of quantitative test methods that can be used to refine, reduce and replace animal testing.
The project is expected to strengthen the competitive position of the Irish bivalve shellfish industry, based on world-class science and food safety. It will provide a scientific basis for rationalising the biotoxin monitoring and risk management systems used in Ireland and the EU, thus supporting the sustainable growth of the shellfish industry while maintaining health and protection for shellfish consumers.
It is also anticipated that the project will contribute to the strengthening of Irish research capacity through the formation of PhDs, and through exchange visits of scientists to national and international hosting laboratories involved in the project.